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MUSCULOSKELETAL ANALYSIS OF HUMAN BODY

Musculoskeletal Analysis of Human Body

Stress-fracture injuries during military training remains a leading health concern for U.S. Service members. In this project, we use an integrated musculoskeletal finite-element model to characterize the kinematics and kinetics of the human body, and use high-resolution medical images to quantify how basic combat training affects the bone (tibia) health of female military recruits.

Publications

Sundaramurthy, A., C. Xu, J. M. Hughes, E. Gaffney-Stomberg, K. I. Guerriere, K. L. Popp, M. L. Bouxsein, J. Reifman, and G. Unnikrishnan. Regional changes in density and microarchitecture in the ultradistal tibia of female recruits after U.S. Army Basic Combat Training. Calcified Tissue International. 2019 July; 105(1):68-76. [PDF, PubMed]

Xu, C., J. Reifman, M. Baggaley, B. W. Edwards, and G. Unnikrishnan. Individual differences in women during walking affect tibial response to load carriage: the importance of individualized musculoskeletal finite-element models. IEEE Transactions on Biomedical Engineering. 2019 May 30; [Epub ahead of print]. [PDF, PubMed]

Popp, K. L., C. Xu, A. Yuan, J. M. Hughes, G. Unnikrishnan, J. Reifman, and M. L. Bouxsein. Trabecular microstructure is influenced by race and sex in Black and White young adults. Osteoporosis International. 2019 January; 30(1):201-209. [PDF, PubMed]

Hughes, J. M., E. Gaffney-Stomberg, K. I. Guerriere, K. M. Taylor, K. L. Popp, C. Xu, G. Unnikrishnan, J. S. Staab, R. W. Matheny, Jr., J. P. McClung, J. Reifman, and M. L. Bouxsein. Changes in tibial bone microarchitecture in female recruits in response to 8 weeks of U.S. Army Basic Combat Training. Bone. 2018 August 1; 113:9-16. [PDF, PubMed]

Unnikrishnan, G., C. Xu, K. L. Popp, J. M. Hughes, A. Yuan, K. I. Guerriere, S. Caksa, K. E. Ackerman, M. L. Bouxsein, and J. Reifman. Regional variation of bone density, microarchitectural parameters, and elastic moduli in the ultradistal tibia of young black and white men and women. Bone. 2018 July 1; 112:194-201. [PDF, PubMed]

Popp, K. L., J. M. Hughes, A. Martinez-Betancourt, M. Scott, V. Turkington, S. Caksa, K. I. Guerriere, K. E. Ackerman, C. Xu, G. Unnikrishnan, J. Reifman, and M. L. Bouxsein. Bone mass, microarchitecture and strength are influenced by race/ethnicity in young adult men and women. Bone. 2017 October; 103:200-208. [PDF, PubMed]

Xu, C., A. Silder, J. Zhang, J. Reifman, and G. Unnikrishnan. A cross-sectional study of the effects of load carriage on running characteristics and tibial mechanical stress: implications for stress-fracture injuries in women. BMC Musculoskeletal Disorders. 2017 March 23; 18:125. [PDF, PubMed]

Xu, C., A. Silder, J. Zhang, J. Hughes, G. Unnikrishnan, J. Reifman, and V. Rakesh. An integrated musculoskeletal-finite-element model to evaluate effects of load carriage on the tibia during walking. Journal of Biomechanical Engineering. 2016 October 1; 138(10):101001. [PDF, PubMed]