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Musculoskeletal Analysis of Human Body

Stress-fracture injuries during military training remains a leading health concern for U.S. Service members. In this project, we use an integrated musculoskeletal finite-element model to characterize the kinematics and kinetics of the human body, and use high-resolution medical images to quantify how basic combat training affects the bone (tibia) health of female military recruits.


Popp, K. L., J. M. Hughes, A. Martinez-Betancourt, M. Scott, V. Turkington, S. Caksa, K. I. Guerriere, K. E. Ackerman, C. Xu, G. Unnikrishnan, J. Reifman, and M. L. Bouxsein. Bone mass, microarchitecture and strength are influenced by race/ethnicity in young adult men and women. Bone. 2017 October; 103:200-208. [PDF]

Xu, C., A. Silder, J. Zhang, J. Reifman, and G. Unnikrishnan. A cross-sectional study of the effects of load carriage on running characteristics and tibial mechanical stress: implications for stress-fracture injuries in women. BMC Musculoskeletal Disorders. 2017 March 23; 18:125. [PDF]

Xu, C., A. Silder, J. Zhang, J. Hughes, G. Unnikrishnan, J. Reifman, and V. Rakesh. An integrated musculoskeletal-finite-element model to evaluate effects of load carriage on the tibia during walking. Journal of Biomechanical Engineering. 2016 October 1; 138(10). [PDF]